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In terms of the mechanism of action, statins can act on the calcium channel subunit Cacna2d3 to reduce calpain 1-mediated myocardial mitochondrial apoptosis, thereby exerting a protective effect against myocardial ischemia-reperfusion injury
Ichijo H, Nshida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K and Gotoh Y
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