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3.3.3 Effect of metformin on birth weight in offspring of patients with polycystic ovary syndrome The progression of the placenta and fetus necessitates a heightened oxygen demand and the presence of fully developed mitochondria in the later stages of pregnancy to facilitate the transportation of essential nutrients for fetal development (Joshi et al., 2022)

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Healthcare providers help patients transition from active optimization to sustainable maintenance protocols that preserve benefits while potentially reducing dose or frequency to optimize cost-effectiveness and long-term compliance