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The work was supported by the Monash University Ramaciotti Centre for Cryo-Electron Microscopy, the Bio21 Ian Holmes Imaging Centre (The University of Melbourne) and the Monash eResearch capabilities, including M3 High-performance computing

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HYALURONIC ACID PREPARATIONS and other hydrogels: these can be injected directly into an affected joint, where they not only increase the viscosity of the joint fluid, thereby increasing lubrication of the joint, but they also deliver or stimulate factors which can have an inhibitory effect on the process of osteoarthritis