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For aged skeletal muscle (satellite cell-adjacent biology), both compounds have relevance but through distinct cellular targets: Epitalon addresses aged satellite cell replicative senescence (TERT in Pax7+ cells), while GHK-Cu addresses myofibre mitochondrial oxidative damage (Nrf2 in MHC+ fibres) a complementary rather than competing biology

These supplements are marketed as 'GLP-1 boosters' or 'GLP-1 support,' but they operate through entirely different biological pathways with far less clinical validation

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You cant really talk about one without the other. As GLP-1 use continues to rise nationwide, Skaff sees both promise and caution