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The classic symptoms of B12 deficiency are persistent fatigue, tingling or numbness in the hands and feet, problems with memory and concentration, mouth ulcers, a sore red tongue, and pale or yellow-tinged skin
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doi:10.1016/j.repbio.2019.07.005
If your supplement contains vitamin B12 or vitamin C, your skin may purge because of these vitamins ability to improve your skin cell turnover rate
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