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The goal is finding a dose that balances effective weight loss with a side-effect profile you can comfortably tolerate long-term
Native polyphenols, such as flavonoids, ellagitannins, phenolic acids, and lignans, are poorly absorbed in their original form and undergo substantial microbial biotransformation in the colon [149, 150]
The SELECT trial enrolled 17,604 patients with a mean body mass index (BMI) of 33.3 and preexisting cardiovascular disease (prior heart attack, stroke, or peripheral artery disease) but no diabetes
This measure has been found to correlate with pill counts [47]
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