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Preparation of nanoparticles P2 (100 mg) or P4 (100 mg) was dissolved in 1 mL DMSO, and the solution were then slowly added dropwise to 10 mL of water
This is often easier when the primary goal is consistency
In practice, the patients most likely to see meaningful improvement are those with clear signs of metabolic dysfunction
Retrospective EHR-based studies can capture real-world associations, yet they are especially vulnerable to residual confounding, treatment-selection bias, differences in healthcare engagement, and unmeasured disease biology
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