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In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1

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Repeat imaging at 612 months helps assess treatment response, with clinically meaningful improvement defined as at least a 30% relative reduction in hepatic fat content