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Nonetheless, considering the clinical relevance of GLP-1 therapies and their potential impact on energy balance beyond food intake and body weight, future studies should investigate whether GLP-1 agonists influence hypothalamic neuropeptide expression or signaling cascades in MC4R-deficient models

More importantly, either SLC7A11 or FSP1 overexpression largely offset the impacts of METTL3 overexpression on ferroptosis of HASMCs treated with cystine deprivation or IKE, which was determined by cell viability, cell death, MDA content and 4-HNE levels (Figure 7C-7I)

Novelty The established literature widely acknowledges GHK-Cus regenerative capacity in skin and systemic wound healing