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Data were analysed offline using AxoGraph X (AxoGraph Scientific)

In the rodent studies, this overgrowth (hyperplasia) eventually led to medullary thyroid tumours

Remarkably, 91% of participants on the highest dose achieved [1] at least 5% weight loss, with 57% reaching 20% or greater weight reduction (Jastreboff et al., NEJM, 2022)