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In cardiac cells, the physical proximity between mitochondria and the sarcoplasmic reticulum (SR, a specific type of ER in heart and skeletal muscle cells) allows the exchange of Ca 2+ in local microdomains, providing rapid Ca 2+ buffering
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45 A barrier to DPP-4 inhibitor use has been the lack of evidence of CV risk reduction in patients with clinical ASCVD
Many plant foods contain antinutrients that can interfere with nutrient absorption.Vitamin D is made from cholesterol, so inadequate cholesterol intake can also impact vitamin D production
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