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In the STEP and SURMOUNT trial programs, participants treated with semaglutide and tirzepatide respectively achieved average weight reductions of 15 to 22% of total body weight, losses that had previously been achievable only through bariatric surgery [8,9]
Food and Drug Administration also warns the drugs may increase the risk of thyroid cancer, acute pancreatitis, gallbladder disease, low blood sugar, kidney injury, damage to the eye's retina and suicidal thinking or behavior, although the risks of serious side effects are small
Depending on your individual makeup and daily habits, the benefits usually hold for anywhere from a few days to a couple of weeks
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