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PMID 21392107
Biochemistry 46 , 90419049 (2007)
reduced cardiac damage following myocardial stress Collateral pathway activation: BPC-157 demonstrated upgrading of minor vessels to compensate for major vessel occlusion Central Nervous System Research Neuroprotection Studies Research in traumatic brain injury and stroke models demonstrated neuroprotective effects from both peptides[14,15]: BPC-157 : Reduced lesion volumes in cortical injury
Prescribers initiating BPC-157 in patients with Child-Pugh A or B hepatic impairment should document: (1) the clinical rationale for peptide therapy, (2) the absence of an FDA-approved alternative for the target condition, (3) baseline hepatic function with planned monitoring intervals, and (4) the patient's informed consent acknowledging the investigational nature of the therapy and the specific evidence limitations in their population
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