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Key safety observations from TRIUMPH-1 Dysaesthesia: An abnormal sensation of touch tingling, numbness, or an altered feeling of normal sensations was reported at higher rates at 9mg and 12mg than at lower doses or with comparator medications
Cutting edge: TLR2 signaling in B cells promotes autoreactivity to DNA via IL-6 secretion
For example, the arousal score of the FSDS-DAO did not show a significant change, which rendered all secondary endpoints exploratory and p-values nominal
Individuals with diabetes have an increased risk of developing neurodegenerative diseases, and the combination of cerebral and peripheral insulin resistance constitutes one of the main mechanisms underlying the initiation and progression of neurodegenerative diseases [23]
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