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This suppresses production of pro-inflammatory cytokines including TNF-alpha, IL-1beta, and IL-6 (the same IL-6 that paradoxically stimulates GLP-1 production in a feedback loop)
Compared to usual care, participants who used GLP-1RAs had a lower risk of: substance use and psychotic disorders seizures neurocognitive disorders including Alzheimers disease and dementia infectious illnesses several respiratory conditions coagulation and cardiometabolic disorders, including deep vein thrombosis, pulmonary embolism, stroke, cardiac arrest, heart failure and myocardial infarction
Other authors declared they had no relevant financial interests
Allergic skin reactions, sometimes temporary, were reported in clinical studies of the drug
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