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Concentration-response values were obtained from the area-under-the-curve (AUC) of the responses elicited by GIP 1-42 , GLP-1 (7-36) NH 2 , glucagon, tirzepatide, non-acylated tirzepatide, peptide 20 or non-lipidated peptide 20
Amylin receptor agonism and metabolic regulation
The CMAJ guidance A guidance article published in the Canadian Medical Association Journal (CMAJ) on glucagon-like peptide-1 receptor agonists during pregnancy and lactation concluded that while the safety data is limited, the pharmacological properties of GLP-1 agonists (large molecular weight, poor oral bioavailability) suggest low theoretical risk during breastfeeding
doi:10.3389/fendo.2026.1291857
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