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Similarly, tobacco exposure also resulted in a significantly higher mRNA expression of PARP, a marker of DNA damage and indicator of apoptosis, 43, 44 suggesting that the more extensive MI in tobacco-exposed rats is also accompanied by an increase in cardiomyocyte apoptosis
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Cameron AJ, Magliano DJ, Zimmet PZ, Welborn T, Shaw JE
Nat Rev Mol Cell Biol 21:363383
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