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Most trials are still ongoing and only one prospective randomized clinical trial with a primary outcome of major cardiovascular events in patients with T2D has reported its results [28]

The formulations designed for oral absorption (arginine salts, absorption enhancers) are attempting to solve this problem, but we dont have human pharmacokinetic studies proving how much actually gets absorbed

While adjusting the medication might be the right move, you might have other options to consider first

Here, we reviewed the therapeutic effects and possible mechanisms of action of GLP-1RAs in the nervous, cardiovascular, and endocrine systems and their correlation with metabolism, tumours and other diseases