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You generally have four options: appeal through the prescribing provider (Ro and PlushCare offer structured appeal support), use a manufacturer direct-to-consumer program (Lilly Direct Zepbound at $499/mo, Novo Direct Wegovy at intro pricing), pay cash retail through Walgreens or GoodRx, or pivot to a compounded cash-pay protocol like PlexusDx Semaglutide Injection ($189/mo) or Tirzepatide Injection ($289/mo)

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Swelling that doesn't improve after 48 hours or bruising that recurs in the exact same spot despite rotating sites should also be evaluated