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Moreover, use in vulnerable populations, including neonates and young children, requires careful riskbenefit evaluation to prevent GI complications and ensure safe administration (567)

Forms of administration and relevance to fertility support: Subcutaneous injection is common in research and allows local delivery near pelvic structures or systemic exposure

Zhao et al., 2021)

A concentration of 10 mM HCl (approximately 0.36 mg/mL HCl in sterile water) is the most widely used reconstitution vehicle for research-grade IGF-1 analogs