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For lupus patients, fatigue is already one of the most common and debilitating symptoms

YZ participated in topic design, manuscript writing, manuscript editing and providing instructional support

Sermorelin is a synthetic analog of growth hormonereleasing hormone (GHRH), specifically representing the first 29 amino acids of the endogenous GHRH sequence

Further data supporting the efficacy of this class of drugs are awaited from two similar ongoing phase III clinical trials: NCT02147925 aims to compare the change of intrahepatic lipids (IHL) in type 2 diabetic patients with non-alcoholic fatty-liver disease after a 26-week treatment of liraglutide, sitagliptin, or insulin glargine per day combined with metformin, while NCT02365233 will assess a similar outcome comparing pioglitazone to DPP-4 inhibitors (sitagliptin or saxagliptin) to insulin glargine