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It also aligns with the observed improvements in cardiometabolic markers seen in clinical trials of incretin-based therapies
Eating smaller, more frequent meals prevents gastric distension and reduces pressure on the lower esophageal sphincter
The medication doesnt suddenly disappear all at once
Three 20-week double-blind, placebo-controlled studies each with 34-week extensions were conducted to evaluate the efficacy and safety of sitagliptin in 410 pediatric patients aged 10 to 17 years with inadequately controlled type 2 diabetes, with or without insulin therapy (HbA1c 6.5-10% for patients not on insulin, HbA1c 7-10% for patients on insulin)
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