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The counterargument: if the patient has plateaued (no weight loss in 4+ weeks despite adherence), switching is reasonable
This is where we must consider bioavailabilitya term we use to describe how well a nutrient is actually absorbed and utilised by the body
There is one small pilot study in humans (examining knee pain, where 7 of 12 participants reported sustained improvement beyond 6 months) and a 2025 safety study confirming BPC-157 was well tolerated in healthy adults
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