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stop at least 2 months before conception Ibuprofen caution / NSAIDs increase GI bleeding risk and may blunt renal function alongside GLP-1 drugs Wegovy FDA label / approved for BMI 30, or 27 with at least one weight-related comorbidity SELECT trial / semaglutide 2.4 mg cut major cardiovascular events by 20% over 3.3 years in adults with obesity Does Caffeine Interfere With GLP-1 Medications
On April 30, 2026, the FDA proposed formally excluding semaglutide, tirzepatide, and liraglutide from the 503B Bulks List - which would eliminate the remaining legal pathway for 503B outsourcing facilities to compound these medications in bulk
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