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Second, we included trials with primary outcomes restricted to changes in HbA1c levels or body weight, which led to missing data from some large sample trials
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At the same time, J&J has submitted an application to the European Medicines Agency (EMA) requesting approval for a new indication for Imbruvica in adults with previously untreated mantle cell lymphoma (MCL) who are eligible for autologous stem cell transplantation
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