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Disrupting GAG biosynthesis or acutely degrading surface GAGs reduces lipoprotein uptake, sensitizes cancer cells to ferroptosis and impairs tumour growth in mice

Meaningful weight loss, typically 5% or more of body weight, tends to become visible by weeks 8 to 12, with the most significant changes continuing to accrue over 6 to 12 months of consistent treatment

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Claire Chang, MD, a board-certified dermatologist based in New York City