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Kawaguchi and Kataoka, 2014)

This finding was consistent among the T2DM-only group, the obesity-only group and the T2DM with obesity group at one, two and three years of follow-up

On November 2023, the United States Food and Drug Administration (FDA) has approved Eli Lilly and Company s Zepbound (tirzepatide) injection, the first and only obesity medication to activate both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors

So far, clinical trials havent resulted in regulatory approval, and pharmaceutical companies havent been motivated to invest in further development