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This peptide was also associated with a reduction in coarse wrinkles and mottled pigmentation

Healthcare providers should document all supplements and compounded preparations patients are using (including full ingredient lists and lot numbers), counsel on proper injection technique and site rotation, and monitor for unexpected adverse effects

**Choose Tirzepatide if** you want higher efficacy than Semaglutide can deliver, you have type 2 diabetes requiring aggressive glucose control, your budget can accommodate slightly higher costs, and you are comfortable with a medication approved since 2022

Eur J Rheumatol Inflamm