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Gclc f/f mice were generated as described 30 and crossed with the Rosa26-CreERT2 mouse strain (Jackson Labs, #008463) or Nrf2 f/f mouse strain (Jackson Labs, #025433)

A multivitamin may be considered for patients with significantly reduced food intake or documented nutritional gaps, though the US Preventive Services Task Force notes insufficient evidence for routine multivitamin use for disease prevention in generally healthy adults

Laboratory medicine , 53 (3), e59e61

In some cases, symptoms are driven more by how the body responds to normal hormonal fluctuations than by abnormal hormone levels themselves.16 Because of this, supplements may be most useful for people dealing with recurring, pattern-based symptoms such as mood changes around the menstrual cycle, persistent fatigue, irregular periods, or hot flashes even when lab values fall within normal ranges