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Melatonin has antioxidant, anti-inflammatory, and immunomodulatory properties beyond its sleep-regulating function, and its age-related decline is associated with deterioration of immune function, sleep quality, and circadian rhythm regulation
J.GrandtD.GoebellH
This interaction is possibly due to the inhibition of organic anion transporting polypeptide (OATP)
Thus, malaria-infected erythrocytes experience eryptosis, which has also been reported in several previous investigations, confirming that eryptosis may, therefore, be a critical defense mechanism against malarial infection or parasitemia
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