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Mechanisms and clinical efficacy of lixisenatide for the management of type 2 diabetes
Consider: Escalating to next dose tier Evaluating adherence and lifestyle factors Checking for medication-interfering conditions (hypothyroidism, PCOS, sleep apnea) Discussing alternative treatments Dose-response comparison table: Wegovy vs Zepbound Data from STEP 1 (Wilding et al., NEJM 2021) and SURMOUNT-1 (Jastreboff et al., NEJM 2022)
4A-C, when compared with the normal group, the levels of LDH, ROS and MDA in the model group were increased
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