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Novo Nordisk has added ileus to the Postmarketing Experience section of the Wegovy label under Gastrointestinal Disorders. In October 2025, Severe Gastrointestinal Adverse Reactions was added to the WARNING AND PRECAUTIONS section of the label
Lopes S, Grand T, Johansen P, Lamotte M, Olivieri AV
Non-pharmacological interventions form the foundation of constipation management in patients taking semaglutide and should be implemented proactively at treatment initiation rather than reactively after symptoms develop
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