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Some prescribers combine the two for enhanced appetite suppression, particularly during weight loss plateaus
Since these compounds in grapefruits greatly decrease the rate of breakdown, repeated doses can lead to much higher doses of the drug in the bloodstream, in turn potentially leading to harmful side effects
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While human data on pathophysiological regulation of these proteins is largely missing, Interleukin-6 13 and bile acids 14 were identified as stimulators besides the classic L-cell activators
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