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In cases of nerve damage such as neuralgia, neuritis, Mortons neuroma, and peripheral neuropathy, injections of a concentrated B12 dose directly surrounding the affected nerve has been shown to promote nerve regeneration and diminish pathologic nerve pain

J Altern Complement Med 2013 May;19(5):459-463

By analyzing the aortic tissue, we found that FOXO4-DRI treatment significantly increased the expression levels of Ki-67 and Lamin B, while reducing the expression of P21, P16, and -H2AX, similar to the results obtained from naturally aged mice (Figure 2A)