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At the start, it is worth knowing that the pivotal trials achieved their results with a single agent plus structured diet and activity support, not with combinations
The STEP-1 trial tested the effect of high-dose semaglutide to produce weight loss in people with obesity who do not have diabetes
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Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits hyperglycemia-induced apoptosis in myocytes by suppressing receptor for advanced glycation end products expression
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