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Since the GLP-1R is highly expressed in the upstream PSN and ZI [66], it would be interesting to determine their neurochemical phenotype and whether they are activated by peripheral GLP-1R agonists to suppress food intake
It also makes GIP and GLP-1 receptors work
When it hits: Often worse in the morning (after overnight electrolyte losses) and after exercise (when sweating accelerates depletion)
GLP-1 agonists can improve insulin sensitivity and lower androgen levels, which may help regulate your periods
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