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By blocking NNMT, you're keeping visceral fat cells in a more reactive state even as overall caloric restriction continues

Patients do not need to take any action and will be given information and support when they attend their next appointment

Cecal samples Cecal weight was measured since the weight of this portion of the intestine appears to be highly influenced by the microbiome (e.g., certain antibiotic treatments dramatically increase cecal weight 27,28,29,30,31 but not the colon 27 )

Lean mass preservation remains relatively good because AOD 9604 selectively targets adipose tissue while tirzepatide maintains favorable lean-to-fat loss ratios