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This includes individuals with severe anxiety or other psychological disorders, thyroid dysfunction, cardiovascular disease, and those who are pregnant or breastfeeding

Summary of Preclinical Research Preclinical observations involving 5-Amino-1MQ in cellular and rodent models include measurements related to metabolic flux, signaling markers within adipose and muscle tissue, and NNMT-regulated transcriptional profiles

Reduced production of acetylcholine has also been found in Parkinson's disease, implicating a role for vitamin B12 deficiency in Parkinson''s Disease (McCarter et al, 2019)

Over-dosing means unnecessary side effects, potentially severe ones like nausea, vomiting, or the kind of gastrointestinal issues that make people quit their protocol entirely