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Key Takeaways Lyophilized peptides unopened: store at 2 to 8 degrees Celsius in the refrigerator for up to 12 to 24 months, or at -20 degrees Celsius in the freezer for 2 or more years

Effectiveness depends on consistent dosing and adherence, not source

This, however, does not apply to other GLP-1RAs approved for the treatment of T2DM, including the same liraglutide (Victoza) and semaglutide (Ozempic or Rybelsus) at lower dosages, prompting several stakeholders to request an updated guidance 232 and more caution in media enthusiasm 233

Tirzepatide may cause serious side effects, including: Possible thyroid tumors, including cancer