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We speculate that IL-1 induces specialized changes in mesangial cell structure and function through direct activation of a transcription factor(s), that result in induction of a specific gene set
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In the Phase II obesity clinical trial MOMENTUM-1, a 2.4 mg dose of pemvidutide resulted in an average weight loss of 15.6% after 48 weeks, with the placebo-corrected figure being 13.4%
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