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Deamidation accelerates at higher temperatures and at pH levels outside the optimal range
Across registered trials, retatrutide has produced the largest weight reductions reported for an incretin-class compound roughly 24% at 12 mg over 48 weeks in phase 2 [1], extended to about 2829% over 6880 weeks in the phase 3 TRIUMPH topline [5], alongside lower HbA1c in type 2 diabetes and large falls in liver-fat content
Ovarian cysts may form from ovarian overstimulation
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