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The engineered drug localized to lipid-rich plaque regions and CD11b/CD11c inflammatory cells, effectively suppressing inflammatory responses and enhancing cholesterol efflux ( By promoting cholesterol efflux and reducing foam-cell content within plaques, GLP-1RA therapy may decrease lipid core size and necrotic burden, thereby stabilizing the fibrous cap, lowering the risk of plaque rupture, and potentially reducing acute coronary events
So far this year, UnitedHealthcare has added 1.1 million members, including nearly 700,000 new lives in its commercial plans, according to the report
While both are GLP-1 receptor agonists, semaglutide has structural modifications that make it more potent and longer-acting