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Individual results may vary based on a wide range of personal factors including but not limited to diet, exercise habits, stress levels, sleep quality, and pre-existing medical conditions
At 5 mg weekly, the SURMOUNT-1 trial showed average weight loss of 16% over 72 weeks
For many, stopping the medication results in the "food noise" returning and weight being regained
However, ingestion of a low fat meal when patients perceived intake of a high fat meal (cognitive factors) did not significantly change the CCK level but was associated with higher symptom scores ( In addition, a CCK antagonist accelerated the gastric emptying rate which could lead to a benefit in both functional dyspepsia as gastroparesis patients (107)
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