doi: 10.3389/fphar.2026.1761748 Received 05 December 2025 Revised 25 March 2026 Accepted 01 April 2026 Published 22 April 2026 Volume 17 - 2026 Edited by Ming Xu, Shimonoseki City University, Japan Reviewed by Gaetano De Siena, University of Florence, Italy Wei Guo, University of North Carolina at Greensboro, United States Updates Copyright 2026 Nandagopal and Manickam
These purified HBs demonstrated robust self-renewal capacity, expanding in a small-molecule-defined medium (ACDFSV) for over 20 passages without losing their proliferative capacity or characteristic morphology

DOI: Published online: December 1, 2020 1 Division of Endocrinology and Metabolism, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea 2 Division of Endocrinology and Metabolism, Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, Korea 3 Division of Endocrinology and Metabolism, Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Seoul, Korea 4 Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea 5 Division of Endocrinology and Metabolism, Department of Internal Medicine, Ajou University School of Medicine, Suwon, Korea 6 Division of Endocrinology and Metabolism, Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Korea Corresponding author: Sung-Woon Kim

Glutathione Skin and Pigmentation Research Small oral and topical studies have reported pigmentation changes, but the evidence does not support broad or injectable skin-lightening claims