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By analyzing recent relevant articles, this study identifies four main ways mitophagy regulates ischemic heart disease: promoting cardiomyocyte hypertrophy and fibrosis, advancing oxidative stress, facilitating inflammation, and inducing cardiomyocyte death ( Fig
KEY POINTS Oxidative stress occurs when there is an imbalance between the production of reactive oxygen species (ROS) and their clearance by antioxidants
C.KetonisC.JonasonJ
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