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In a systematic review of patients suffering from cholestatic liver disease, those treated with a combination of Ursodeoxycholic acid (UDCA) and 1,200 mg/day of SAMe achieved a significantly higher "total effective rate" regarding improved liver enzymes and reduced clinical symptoms (such as severe itching and fatigue) compared to those receiving UDCA monotherapy
(30,31) The authors acknowledged several limitations, including the use of a national patient database, which restricted their ability to control for prior diabetes management and preoperative glycemic control
Is Henry Meds safe
Biol Chem Hoppe Seyler (1991) 372:30511
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