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Human Psychopharmacology: Clinical and Experimental, 24(3), 177190
New oral GLP-1 formslike drops and lozengesshow promising results, though injectable GLP-1s still have the most clinical data for significant weight loss
However, liraglutide achieved this primarily through a pronounced reduction in palatable food intake, whereas sibutramine reduced consumption of both chow and palatable foods (Hansen et al., 2012)
Participants were randomly assigned in a 1:1:1:3 ratio to receive subcutaneous injections of tirzepatide once per week at doses of 5 mg, 10 mg, or 15 mg, or insulin glargine (100 U/mL)
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