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Notable heterogeneity was observed in cellular responses to the GPX4-targeting ferroptotic inducers RSL3 9 and ML210 9,29,30 (Supplementary Fig
For example, a 2021 review discussed possible ways NAC could help counter ROS-related survival, metastasis, and drug-resistance pathways in triple-negative breast cancer.39 And in a small uncontrolled pilot study involving women with breast cancer, NAC supplementation was associated with reduced markers of tumor cell proliferation.40 But animal research has found concerning effects in other contexts
Bridge RNAs direct programmable recombination of target and donor DNA
