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Ascorbate, dithiothreitol and TCEP all reduce copper(II) to copper(I), and the donor arrangement in this tripeptide stabilizes the divalent ion specifically

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It has been observed in animal studies that adenovirus DNA vector without a replicating E1 gene can remain transcriptionally active in the body for months after vaccination (86) whereas in the case of mRNA vaccines, the RNA is rapidly degraded (87, 88)

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