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Transcellular permeability Given the integrity of cellular structures and junctional proteins between ECs, it is typical for gases and small lipid-soluble molecules with molecular weights under 400 Da to be able to passively diffuse across the BBB [22]

Basic Fibroblast Growth Factor (bFGF) related decapeptide 0.1% solution, with tacrolimus 0.1% ointment combination therapy compared with tacrolimus 0.1% ointment monotherapy in the treatment of stable vitiligo: a phase IV, randomized 12 months Study

Considerations: As with any copper-containing compound, there is a theoretical concern about copper toxicity with excessive systemic administration

Resume injections after the break at the same or slightly reduced dose